About Enhancer
| Enhancer ID: | E_00251 |
| Species: | Homo sapiens |
| Position : | chr6:135644579-135645062   |
| Year: | 2023 |
| Title: | Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | T-cell acute lymphoblastic leukemia |
| PMID: | 36949154 |
| MONDO: | MONDO:0004947 |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | DND-41 |
| CVCL ID: | CVCL_2022 |
| Cell Type: | T lymphoblast |
| Cell Ontology ID: | CL:0002419 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, 4C-seq |
About Target Gene
| Target gene : | MNX1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00216 | chr6:135640000-135645000 | Prostate | patient-derived xenograft cell | prostate cancer |
Expression of Target Genes for the Enhancer