Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00272
Species: Homo sapiens
Position : chr3:111274086-111275786
Year: 2025
Title: Enhancer activation from transposable elements in extrachromosomal DNA
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  41120733
MONDO: MONDO:0011998
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: Hi-C, ATAC-seq
Low Throughput Method: Luciferase reporter assay, CRISPR knockout, CRISPRi, ORCA
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00094 chr3:111274001-111275000 Colon colorectal carcinoma cell line Colorectal adenocarcinoma
E_00095 chr3:111274001-111275000 Colon colorectal carcinoma cell line Colorectal adenocarcinoma
Expression of Target Genes for the Enhancer