About Enhancer
| Enhancer ID: | E_00274 |
| Species: | Homo sapiens |
| Position : | chr2:177480000-177490000   |
| Year: | 2022 |
| Title: | Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 35390275 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Normal human astrocytes |
| CVCL ID: | |
| Cell Type: | astrocyte |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | RNA-seq, Hi-C, 4C-seq, ChIP-seq |
| Low Throughput Method: | RT-RT-qPCR, CRISPRa, siRNA Knockdown, smFISH |
About Target Gene
| Target gene : | LINC01116 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00275 | chr2:177480000-177490000 | Aorta | aortic endothelial cell | -- |
Expression of Target Genes for the Enhancer