About Enhancer
| Enhancer ID: | E_00283 |
| Species: | Homo sapiens |
| Position : | chr19:50913170-50987888   |
| Year: | 2023 |
| Title: | Complementary Alu sequences mediate enhancer-promoter selectivity |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | T-cell acute lymphoblastic leukemia |
| PMID: | 37438529 |
| MONDO: | MONDO:0004947 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Human T-ALL cell |
| CVCL ID: | |
| Cell Type: | T lymphoblast |
| Cell Ontology ID: | CL:0002419 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C |
| Low Throughput Method: | CRISPR Knockout, 3C-RT-qPCR, qRT-PCR, FISH |
About Target Gene
| Target gene : | POLRMT |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00280 | chr19:50913170-50987888 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_00281 | chr19:50913170-50987888 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_00282 | chr19:50913170-50987888 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_00285 | chr19:50913170-50987888 | Lung | non-small cell lung carcinoma cell | non-small cell lung carcinoma |
Expression of Target Genes for the Enhancer