About Enhancer
| Enhancer ID: | E_00286 |
| Species: | Homo sapiens |
| Position : | chr11:68155000-68173900   |
| Year: | 2025 |
| Title: | Functional variant rs9344 at 11q133 regulates CCND1 expression in multiple myeloma with t(11;14) |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 39402215 |
| MONDO: | |
| Tissue: | Embryonic Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | HEK293T |
| CVCL ID: | CVCL_0063 |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, RNA-seq, Hi-C |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR, Western blot |
About Target Gene
| Target gene : | CCND1 |
About TF
| TF name : | PAX5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| PAX5 | C-MYB transcription factor network | pid | 87 |
| PAX5 | ID | netpath | 38 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer