About Enhancer
| Enhancer ID: | E_00289 |
| Species: | Homo sapiens |
| Position : | chr10:89912175-89913031   |
| Year: | 2023 |
| Title: | Landscape of enhancer disruption and functional screen in melanoma cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | pancreatic ductal adenocarcinoma |
| PMID: | 37904237 |
| MONDO: | MONDO:0005147 |
| Tissue: | Pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | PANC-1 |
| CVCL ID: | CVCL_0480 |
| Cell Type: | pancreatic ductal adenocarcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, CRISPRi Screen |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPRi, CRISPRa, RT-RT-qPCR, Western blot, Cell Apoptosis Assay, Colony Formation Assay |
About Target Gene
| Target gene : | PTEN |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer