Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00290
Species: Homo sapiens
Position : chr5:74678000-74688000
Year: 2021
Title: Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: skin melanoma
PMID:  34362881
MONDO: MONDO:0005105
Tissue: Skin
Tissue Ontology ID: UBERON:0000014
Cell Source: Melanoma cell line
CVCL ID:
Cell Type: melanoma cell
Cell Ontology ID: CL:0002573
Experiment Type: Functional perturbation assay, Enhancer activity assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: CRISPR Knockout, RT-RT-qPCR, Western blot
About Target Gene
Target gene : ENC1
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_00442 chr5:74680400-74682399 Breast breast carcinoma cell breast carcinoma
E_00443 chr5:74682400-74683933 Breast breast carcinoma cell breast carcinoma
E_00444 chr5:74686000-74687899 Breast breast carcinoma cell breast carcinoma
Expression of Target Genes for the Enhancer