Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00318
Species: Homo sapiens
Position : chr2:176265000-176270000
Year: 2022
Title: EWS::FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  35653119
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K562 erythroleukemia cells
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, Hi-C
Low Throughput Method: ChIP-RT-qPCR, CRISPR Knockout, CRISPRi, RT-RT-qPCR
About Target Gene
Target gene : HOXD13
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_00317 chr2:176265000-176270000 Heart cardiomyocyte --
Expression of Target Genes for the Enhancer