About Enhancer
| Enhancer ID: | E_00320 |
| Species: | Homo sapiens |
| Position : | chr11:5225000-5225500   |
| Year: | 2020 |
| Title: | Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32293525 |
| MONDO: | |
| Tissue: | Embryonic Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | Human embryonic kidney cell |
| CVCL ID: | |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, QHR-4C |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knock-in, RT-RT-qPCR |
About Target Gene
| Target gene : | HBG2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00972 | chr11:5224750-5226210 | Bladder | bladder carcinoma cell | bladder carcinoma |
| E_00974 | chr11:5224750-5226210 | Bone Marrow | chronic myeloid leukemia cell | chronic myeloid leukemia |
| E_00822 | chr11:5225000-5227000 | Bone Marrow | CD34-positive hematopoietic stem cell | -- |
| E_00954 | chr11:5225000-5227000 | Breast | breast carcinoma cell | breast carcinoma |
| E_00973 | chr11:5225400-5225774 | Bone Marrow | chronic myeloid leukemia cell | chronic myeloid leukemia |
Expression of Target Genes for the Enhancer