About Enhancer
| Enhancer ID: | E_00353 |
| Species: | Homo sapiens |
| Position : | chr12:52304911-53120196   |
| Year: | 2019 |
| Title: | SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ER??-positive breast cancer |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 31073170 |
| MONDO: | MONDO:0006120 |
| Tissue: | Breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MCF7 |
| CVCL ID: | CVCL_0031 |
| Cell Type: | breast carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C, DHS-seq |
| Low Throughput Method: | ChIP-RT-qPCR, CRISPRi, qRT-PCR, RNA-FISH, ChIA-PET |
About Target Gene
| Target gene : | KRT80 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer