Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00355
Species: Homo sapiens
Position : chr10:102880001-102881789
Year: 2023
Title: A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
Genome Build: hg19
Enhancer Type: Super-enhancer
Condition: Disease
Disease Name: pancreatic ductal adenocarcinoma
PMID:  37673892
MONDO: MONDO:0005147
Tissue: Pancreas
Tissue Ontology ID: UBERON:0001264
Cell Source: MIA PaCa-2
CVCL ID: CVCL_0428
Cell Type: pancreatic ductal adenocarcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-seq, ATAC-seq, RNA-seq
Low Throughput Method: CRISPR Knockout, qRT-PCR, Western blot
About Target Gene
Target gene : HNRNPF
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer