About Enhancer
| Enhancer ID: | E_00363 |
| Species: | Homo sapiens |
| Position : | chr20:48900221-48901229   |
| Year: | 2019 |
| Title: | Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | hepatocellular carcinoma |
| PMID: | 30659195 |
| MONDO: | MONDO:0007256 |
| Tissue: | Liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | Hepatocellular carcinoma cell line (HepG2) |
| CVCL ID: | CVCL_0027 |
| Cell Type: | hepatocellular carcinoma cell |
| Cell Ontology ID: | CL:0000182 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay |
| High Throughput Method: | ChIP-seq, RNA-seq, WGBS |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | CEBFB |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00836 | chr20:48400000-49200000 | Breast | breast carcinoma cell | breast carcinoma |
| E_00837 | chr20:48400000-49200000 | Breast | breast carcinoma cell | breast carcinoma |
| E_03491 | chr20:48900221-48901229 | Liver | hepatocyte | -- |
| E_03512 | chr20:48900221-48901229 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
| E_03513 | chr20:48900221-48901229 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
Expression of Target Genes for the Enhancer