About Enhancer
| Enhancer ID: | E_00366 |
| Species: | Homo sapiens |
| Position : | chr12:12874700-12875275   |
| Year: | 2021 |
| Title: | Lupus susceptibility region containing CDKN1B rs34330 mechanistically influences expression and function of multiple target genes, also linked to proliferation and apoptosis |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 33982894 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Primary B cells |
| CVCL ID: | |
| Cell Type: | B cell |
| Cell Ontology ID: | CL:0000945 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, 3C-RT-qPCR, CRISPR Knockout, CRISPRi, RT-RT-qPCR |
About Target Gene
| Target gene : | DDX47 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00364 | chr12:12874700-12875275 | Embryonic Kidney | embryonic kidney cell | -- |
| E_00365 | chr12:12874700-12875275 | Blood | T lymphoblast | T-cell acute lymphoblastic leukemia |
| E_00367 | chr12:12874700-12875275 | Blood | T cell | -- |
| E_00995 | chr12:12874700-12875275 | Colon | colorectal adenocarcinoma cell | colorectal adenocarcinoma |
Expression of Target Genes for the Enhancer