About Enhancer
| Enhancer ID: | E_00379 |
| Species: | Mus musculus |
| Position : | chr12:85463935-85468299   |
| Year: | 2016 |
| Title: | Stimulus-specific combinatorial functionality of neuronal c-fos enhancers. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26595656 |
| Tissue: | cerebral cortex |
| Tissue Ontology ID: | UBERON:0000956 |
| Cell Source: | Primary mouse cortical neurons |
| Cell Type: | neuron |
| Cell Ontology ID: | CL:0000540 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Enhancer RNA assay; Chromatin interaction assay; Functional perturbation assay |
| High Throughput Method: | NPAS4 ChIP-seq; activity-regulated TF ChIP-seq; RNA-seq |
| Low Throughput Method: | Luciferase reporter assay; eRNA RT-qPCR; NPAS4 knockdown; CRISPRi; 3C; Fos pre-mRNA RT-qPCR |
About Target Gene
| Target gene : | Fos |
About TF
| TF name : | Npas4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00064 | chr12:85463935-85468299 | brain | neuron | NA |
| E_00065 | chr12:85463935-85468299 | brain | neuron | NA |
| E_00356 | chr12:85466416-85469570 | brain | NA | NA |
| E_00357 | chr12:85466416-85469570 | brain | NA | NA |
| E_00358 | chr12:85466416-85469570 | brain | NA | NA |
| E_00359 | chr12:85466416-85469570 | brain | NA | NA |
| E_00360 | chr12:85466416-85469570 | brain | NA | NA |
| E_00361 | chr12:85466416-85469570 | brain | NA | NA |
Expression of Target Genes for the Enhancer