About Enhancer
| Enhancer ID: | E_00381 |
| Species: | Homo sapiens |
| Position : | chr8:128662857-128663857   |
| Year: | 2014 |
| Title: | Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal carcinoma |
| PMID: | 24662484 |
| MONDO: | MONDO:0005132 |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | SW480 |
| CVCL ID: | CVCL_0546 |
| Cell Type: | colorectal carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 3C-seq |
| Low Throughput Method: | FISH, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, RNA Immunoprecipitation |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | CTCF; TCF4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
6 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00908 | chr8:128311200-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00845 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00846 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00847 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00848 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00380 | chr8:128662857-128663857 | Colon | colorectal carcinoma cell | colorectal carcinoma |
Expression of Target Genes for the Enhancer