About Enhancer
| Enhancer ID: | E_00382 |
| Species: | Homo sapiens |
| Position : | chr12:85074370-85074815   |
| Year: | 2020 |
| Title: | Generation of onco-enhancer enhances chromosomal remodeling and accelerates tumorigenesis |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | skin melanoma |
| PMID: | 33196849 |
| MONDO: | MONDO:0005105 |
| Tissue: | Skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | |
| CVCL ID: | |
| Cell Type: | |
| Cell Ontology ID: | |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 3C-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, 3C assay, qRT-PCR, Western blot |
About Target Gene
| Target gene : | NTS |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00292 | chr12:85074000-85075186 | Colon | colorectal carcinoma cell | colorectal cancer |
Expression of Target Genes for the Enhancer