About Enhancer
| Enhancer ID: | E_00383 |
| Species: | Homo sapiens |
| Position : | chr1:22101842-22103407   |
| Year: | 2017 |
| Title: | Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 28536097 |
| MONDO: | |
| Tissue: | Umbilical vein |
| Tissue Ontology ID: | UBERON:0002066 |
| Cell Source: | HUVEC |
| CVCL ID: | CVCL_2959 |
| Cell Type: | umbilical vein endothelial cell |
| Cell Ontology ID: | CL:0002615 |
| Experiment Type: | Enhancer functional assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay |
About Target Gene
| Target gene : | HLX |
About TF
| TF name : | ERG |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ERG | ERK cascade ( FGF8 signaling (Mouse) ) | inoh | 17 |
| ERG | ERK cascade ( FGF8 signaling (Xenopus) ) | inoh | 17 |
| ERG | FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) | inoh | 20 |
| ERG | FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) | inoh | 18 |
| ERG | PDGF signaling pathway | panther | 113 |
| ERG | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer