About Enhancer
| Enhancer ID: | E_00396 |
| Species: | Homo sapiens |
| Position : | chr4:70849125-70849971   |
| Year: | 2019 |
| Title: | Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | salivary gland acinic cell carcinoma |
| PMID: | 30664630 |
| MONDO: | MONDO:0006002 |
| Tissue: | Salivary Gland |
| Tissue Ontology ID: | UBERON:0001044 |
| Cell Source: | AciCC primary tumor cells |
| CVCL ID: | |
| Cell Type: | acinic cell carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C, WGS |
| Low Throughput Method: | Luciferase Reporter Assay, FISH, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | NR4A3 |
About TF
| TF name : | NR4A3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NR4A3 | Nuclear Receptor transcription pathway | reactome | 51 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer