Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00397
Species: Homo sapiens
Position : chr4:70849125-70849971
Year: 2019
Title: Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  30664630
MONDO:
Tissue: Salivary Gland
Tissue Ontology ID: UBERON:0001044
Cell Source: normal parotid gland cells
CVCL ID:
Cell Type: parotid gland cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay
High Throughput Method: ChIP-seq, RNA-seq, Hi-C, WGS
Low Throughput Method: Luciferase Reporter Assay, FISH, RT-RT-qPCR, Western blot
About Target Gene
Target gene : NR4A3
About TF
TF name : NR4A3
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
NR4A3 Nuclear Receptor transcription pathway reactome 51
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00395 chr4:70849125-70849971 Embryonic Kidney embryonic kidney cell --
E_00396 chr4:70849125-70849971 Salivary Gland acinic cell carcinoma cell salivary gland acinic cell carcinoma
Expression of Target Genes for the Enhancer