Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00400
Species: Homo sapiens
Position : chr11:5246600-5247600
Year: 2020
Title: Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  32293525
MONDO:
Tissue: Embryonic Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK-293T
CVCL ID: CVCL_0063
Cell Type: embryonic kidney cell
Cell Ontology ID: CL:0002139
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, QHR-4C
Low Throughput Method: CRISPR Knock-in
About Target Gene
Target gene : HBB
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_01240 chr11:5241525-5251525 Bone marrow erythroblast --
E_01117 chr11:5246500-5247000 Breast breast carcinoma cell breast carcinoma
E_00399 chr11:5246600-5247600 Bone Marrow chronic myeloid leukemia cell chronic myeloid leukemia
Expression of Target Genes for the Enhancer