Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00402
Species: Homo sapiens
Position : chr7:92384001-92385000
Year: 2025
Title: Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  40162972
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: HSPCs
CVCL ID:
Cell Type: hematopoietic stem cell
Cell Ontology ID: CL:0001029
Experiment Type: Functional perturbation assay, Chromatin interaction assay
High Throughput Method: ATAC-seq, ACT-seq, 4C-seq, RNA-seq
Low Throughput Method: CRISPR knockout, CRISPRi, RT-RT-qPCR
About Target Gene
Target gene : MNX1
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00448 chr7:92350000-92450000 Peripheral Blood chronic myeloid leukemia cell chronic myeloid leukemia
E_00401 chr7:92384001-92385000 Blood induced pluripotent stem cell --
Expression of Target Genes for the Enhancer