About Enhancer
| Enhancer ID: | E_00411 |
| Species: | Homo sapiens |
| Position : | chr17:48100000-48130000   |
| Year: | 2024 |
| Title: | Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | skin melanoma |
| PMID: | 38488867 |
| MONDO: | MONDO:0005105 |
| Tissue: | Skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | WM1552C |
| CVCL ID: | |
| Cell Type: | melanoma cell |
| Cell Ontology ID: | CL:0002573 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | ITGA3 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00412 | chr17:48100000-48130000 | Skin | melanoma cell | skin melanoma |
| E_00413 | chr17:48100000-48130000 | Skin | melanoma cell | skin melanoma |
| E_00949 | chr17:48105016-48105270 | Lung | lung adenocarcinoma cell | lung adenocarcinoma |
| E_00357 | chr17:48110000-48150000 | Skin | melanoma cell | skin melanoma |
Expression of Target Genes for the Enhancer