Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00438
Species: Homo sapiens
Position : chr2:213700000-214600000
Year: 2024
Title: Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: T-cell acute lymphoblastic leukemia
PMID:  39277592
MONDO: MONDO:0004947
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: DND41
CVCL ID: CVCL_A296
Cell Type: T lymphoblast
Cell Ontology ID: CL:0002419
Experiment Type: Chromatin interaction assay, Functional perturbation assay
High Throughput Method: Hi-C, ATAC-seq, H3K27ac ChIP-seq, H3K27me3 CUT&RUN, RNA-seq
Low Throughput Method: Oligopaint DNA FISH, RT-RT-qPCR
About Target Gene
Target gene : IKZF2
About TF
TF name :
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer