About Enhancer
| Enhancer ID: | E_00447 |
| Species: | Homo sapiens |
| Position : | chr6:156425000-156525000   |
| Year: | 2021 |
| Title: | The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic myeloid leukemia |
| PMID: | 34584081 |
| MONDO: | MONDO:0011998 |
| Tissue: | Peripheral Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | chronic myeloid leukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, 3C-seq |
| Low Throughput Method: | RT-RT-qPCR, FISH |
About Target Gene
| Target gene : | EVI1 |
About TF
| TF name : | CTCF; GATA2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer