About Enhancer
| Enhancer ID: | E_00453 |
| Species: | Homo sapiens |
| Position : | chr19:33790834-33791348   |
| Year: | 2019 |
| Title: | HoxA9 binds and represses the Cebpa +8 kb enhancer |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | acute myeloid leukemia |
| PMID: | 31120998 |
| MONDO: | MONDO:0018874 |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | MUTZ-3 |
| CVCL ID: | CVCL_1435 |
| Cell Type: | myeloid leukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay, EMSA |
About Target Gene
| Target gene : | CEBPA |
About TF
| TF name : | HOXA9 |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HOXA9 | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00522 | chr19:33790000-33792000 | Bone marrow | mesenchymal stem cell | -- |
Expression of Target Genes for the Enhancer