Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00454
Species: Homo sapiens
Position : chr8:128835000-128837000
Year: 2014
Title: Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal carcinoma
PMID:  24662484
MONDO: MONDO:0005132
Tissue: Colon
Tissue Ontology ID: UBERON:0001155
Cell Source: HCT116
CVCL ID: CVCL_0291
Cell Type: colorectal carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase Reporter Assay, RT-RT-qPCR, siRNA Knockdown
About Target Gene
Target gene : CCAT1-L
About TF
TF name : CTCF; TCF7L2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_00167 chr8:128750000-129000000 Breast breast carcinoma cell breast carcinoma
Expression of Target Genes for the Enhancer