About Enhancer
| Enhancer ID: | E_00457 |
| Species: | Homo sapiens |
| Position : | chr22:39385500-39387500   |
| Year: | 2022 |
| Title: | B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 35778390 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Normal B cells |
| CVCL ID: | |
| Cell Type: | B cell |
| Cell Ontology ID: | CL:0000945 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | CUT&Tag, ATAC-seq, Hi-C, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, qRT-PCR, Western blot |
About Target Gene
| Target gene : | APOBEC3C |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00510 | chr22:39385500-39387500 | Blood | B cell | chronic lymphocytic leukemia |
Expression of Target Genes for the Enhancer