About Enhancer
| Enhancer ID: | E_00458 |
| Species: | Homo sapiens |
| Position : | chr7:117074000-117077000   |
| Year: | 2016 |
| Title: | CFTR regulatory elements identified by 5C |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 26615198 |
| MONDO: | |
| Tissue: | Nasal epithelium |
| Tissue Ontology ID: | UBERON:0005384 |
| Cell Source: | HNECs |
| CVCL ID: | |
| Cell Type: | nasal epithelial cell |
| Cell Ontology ID: | CL:1001567 |
| Experiment Type: | Chromatin interaction assay |
| High Throughput Method: | Hi-C, ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | SMARCC1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SMARCC1 | AndrogenReceptor | netpath | 167 |
| SMARCC1 | Glucocorticoid receptor regulatory network | pid | 85 |
| SMARCC1 | Regulation of Androgen receptor activity | pid | 54 |
| SMARCC1 | RMTs methylate histone arginines | reactome | 75 |
| SMARCC1 | TNFalpha | netpath | 274 |
| SMARCC1 | Wnt signaling pathway | panther | 250 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00893 | chr7:117075400-117076000 | Bronchus | bronchial epithelial cell | -- |
Expression of Target Genes for the Enhancer