Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00480
Species: Homo sapiens
Position : chr18:57075464-57076425
Year: 2019
Title: A Cohesin-Mediated Intrachromosomal Loop Drives Oncogenic ROR lncRNA to Accelerate Tumorigenesis
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal adenocarcinoma
PMID:  31451355
MONDO: MONDO:0005132
Tissue: Colon
Tissue Ontology ID: UBERON:0001155
Cell Source: HT29
CVCL ID: CVCL_0320
Cell Type: colorectal adenocarcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, 3C-RT-qPCR, CRISPR Knockout, RT-RT-qPCR, Western blot
About Target Gene
Target gene : ROR
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00479 chr18:57075464-57076425 Stomach gastric adenocarcinoma cell gastric adenocarcinoma
E_00481 chr18:57075464-57076425 Uvea uveal melanoma cell uveal melanoma
Expression of Target Genes for the Enhancer