About Enhancer
| Enhancer ID: | E_00488 |
| Species: | Homo sapiens |
| Position : | chr15:38850022-38850502   |
| Year: | 2019 |
| Title: | Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31164884 |
| MONDO: | |
| Tissue: | Embryonic Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | HEK293 |
| CVCL ID: | CVCL_0045 |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, EMSA, ChIP-RT-qPCR, Western blot, RT-RT-qPCR |
About Target Gene
| Target gene : | RASGRP1 |
About TF
| TF name : | HNRNP-K |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer