About Enhancer
| Enhancer ID: | E_00502 |
| Species: | Homo sapiens |
| Position : | chr8:128744932-128746104   |
| Year: | 2025 |
| Title: | Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 41266362 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | MDA PCa 2B cells |
| CVCL ID: | CVCL_4740 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | Luciferase reporter assay, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | NDRG1 |
About TF
| TF name : | FOXA1 |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXA1 | AndrogenReceptor | netpath | 167 |
| FOXA1 | Direct p53 effectors | pid | 141 |
| FOXA1 | FOXA1 transcription factor network | pid | 45 |
| FOXA1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| FOXA1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
3 found
Expression of Target Genes for the Enhancer