About Enhancer
| Enhancer ID: | E_00505 |
| Species: | Homo sapiens |
| Position : | chr6:396143-396593   |
| Year: | 2020 |
| Title: | Cross-species analysis of enhancer logic using deep learning |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | skin melanoma |
| PMID: | 32732264 |
| MONDO: | MONDO:0005105 |
| Tissue: | Skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | Human melanoma cell |
| CVCL ID: | |
| Cell Type: | melanoma cell |
| Cell Ontology ID: | CL:0002573 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay |
About Target Gene
| Target gene : | IRF4 |
About TF
| TF name : | SOX10 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SOX10 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00936 | chr6:396135-396636 | Skin | melanoma cell | skin melanoma |
Expression of Target Genes for the Enhancer