About Enhancer
| Enhancer ID: | E_00509 |
| Species: | Homo sapiens |
| Position : | chr16:1480850-1482378   |
| Year: | 2019 |
| Title: | Noncoding deletions reveal a gene that is critical for intestinal function |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31217582 |
| MONDO: | |
| Tissue: | Stomach |
| Tissue Ontology ID: | UBERON:0000945 |
| Cell Source: | Gastrointestinal epithelial cells |
| CVCL ID: | |
| Cell Type: | gastrointestinal epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | WGS, WES, RNA-seq, ChIP-seq |
| Low Throughput Method: | Transgenic Reporter Assay, CRISPR Knockout, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | LACZ |
About TF
| TF name : | FOXA1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXA1 | AndrogenReceptor | netpath | 167 |
| FOXA1 | Direct p53 effectors | pid | 141 |
| FOXA1 | FOXA1 transcription factor network | pid | 45 |
| FOXA1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| FOXA1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00796 | chr16:1480850-1482378 | Gastrointestinal Tract | enteroendocrine cell | -- |
Expression of Target Genes for the Enhancer