About Enhancer
| Enhancer ID: | E_00529 |
| Species: | Homo sapiens |
| Position : | chr1:185660000-185710000   |
| Year: | 2024 |
| Title: | Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | nasopharyngeal carcinoma |
| PMID: | 38490101 |
| MONDO: | MONDO:0005350 |
| Tissue: | Nasopharyngeal epithelium |
| Tissue Ontology ID: | UBERON:0008338 |
| Cell Source: | C666-1 |
| CVCL ID: | CVCL_7949 |
| Cell Type: | nasopharyngeal carcinoma cell |
| Cell Ontology ID: | CL:0000069 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C, 4C-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | siRNA Knockdown, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | PTGS2 |
About TF
| TF name : | SMAD3; REL |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer