About Enhancer
| Enhancer ID: | E_00538 |
| Species: | Homo sapiens |
| Position : | chr10:92680870-92681128   |
| Year: | 2015 |
| Title: | Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 26257940 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | VCaP cells |
| CVCL ID: | CVCL_2235 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay |
About Target Gene
| Target gene : | ANKRD1 |
About TF
| TF name : | TEAD4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TEAD4 | PPARA activates gene expression | reactome | 113 |
| TEAD4 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | reactome | 29 |
| TEAD4 | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer