About Enhancer
| Enhancer ID: | E_00554 |
| Species: | Homo sapiens |
| Position : | chr1:165355703-165356702   |
| Year: | 2016 |
| Title: | Active medulloblastoma enhancers reveal subgroup-specific cellular origins |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | medulloblastoma |
| PMID: | 26814967 |
| MONDO: | MONDO:0005146 |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Primary Medulloblastoma Tissue (Group4 subgroup) |
| CVCL ID: | |
| Cell Type: | medulloblastoma cell |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Transgenic Reporter Assay, CRISPR Knockout, RT-RT-qPCR, Western blot, Immunofluorescence |
About Target Gene
| Target gene : | LMX1A |
About TF
| TF name : | LMX1A |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| LMX1A | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer