About Enhancer
| Enhancer ID: | E_00597 |
| Species: | Homo sapiens |
| Position : | chr5:159927785-159928129   |
| Year: | 2023 |
| Title: | Three-Dimensional Chromosomal Landscape Revealing miR-146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR-Mediated Approach to Inhibit the Interferon Pathway |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 37728419 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | LNCaP95 |
| CVCL ID: | CVCL_WK56 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | Hi-C, ATAC-seq |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, RT-RT-qPCR |
About Target Gene
| Target gene : | MIR146A |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer