Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00599
Species: Homo sapiens
Position : chr13:27950000-27980000
Year: 2022
Title: Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: small cell lung carcinoma
PMID:  35316324
MONDO: MONDO:0005020
Tissue: Lung
Tissue Ontology ID: UBERON:0002048
Cell Source: H128
CVCL ID: CVCL_1491
Cell Type: small cell lung carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Histone modification ChIP-seq, Chromosome conformation capture sequencing, CRISPR interference
High Throughput Method: H3K27ac ChIP-seq, H3K4me3 ChIP-seq, ATAC-seq, 4C-seq
Low Throughput Method: RT-RT-qPCR, Western blot
About Target Gene
Target gene : CDX2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00600 chr13:27950000-27980000 Bone Marrow B lymphoblast B-cell acute lymphoblastic leukemia
E_00601 chr13:27950000-27980000 Bone Marrow B lymphoblast B-cell acute lymphoblastic leukemia
Expression of Target Genes for the Enhancer