Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00600
Species: Homo sapiens
Position : chr13:27950000-27980000
Year: 2022
Title: Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: B-cell acute lymphoblastic leukemia
PMID:  35316324
MONDO: MONDO:0004945
Tissue: Bone Marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: NALM16
CVCL ID: CVCL_1891
Cell Type: B lymphoblast
Cell Ontology ID: CL:0000945
Experiment Type: Histone modification ChIP-seq, Chromosome conformation capture sequencing, CRISPR interference
High Throughput Method: H3K27ac ChIP-seq, H3K4me3 ChIP-seq, ATAC-seq, 4C-seq
Low Throughput Method: RT-RT-qPCR, Western blot
About Target Gene
Target gene : PAN3
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00599 chr13:27950000-27980000 Lung small cell lung carcinoma cell small cell lung carcinoma
E_00601 chr13:27950000-27980000 Bone Marrow B lymphoblast B-cell acute lymphoblastic leukemia
Expression of Target Genes for the Enhancer