About Enhancer
| Enhancer ID: | E_00606 |
| Species: | Homo sapiens |
| Position : | chr8:128751884-128753219   |
| Year: | 2025 |
| Title: | Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 41266362 |
| MONDO: | |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Normal colon epithelial cells |
| CVCL ID: | |
| Cell Type: | colon epithelial cell |
| Cell Ontology ID: | CL:1000348 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ATAC-seq, RNA-seq |
| Low Throughput Method: | Luciferase reporter assay, RT-RT-qPCR |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00419 | chr8:128740000-128790000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00112 | chr8:128745000-128752600 | Epithelium | breast epithelial cell | Cancer |
| E_00646 | chr8:128747000-128753000 | Blood | T lymphoblast | T-cell acute lymphoblastic leukemia |
| E_00945 | chr8:128747680-128753680 | Bone marrow | acute myeloid leukemia cell | acute myeloid leukemia |
| E_00595 | chr8:128748351-128800823 | Pulmonary artery | pulmonary artery endothelial cell | -- |
| E_00596 | chr8:128748351-128800823 | Prostate | prostate carcinoma cell | prostate cancer |
| E_00167 | chr8:128750000-129000000 | Breast | breast carcinoma cell | breast carcinoma |
| E_01293 | chr8:128753000-128754000 | Endometrium | endometrial adenocarcinoma cell | endometrial adenocarcinoma |
Expression of Target Genes for the Enhancer