About Enhancer
| Enhancer ID: | E_00612 |
| Species: | Homo sapiens |
| Position : | chr4:75746565-75746914   |
| Year: | 2019 |
| Title: | The SNP of rs6854845 suppresses transcription via the DNA looping structure alteration of super-enhancer in colon cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31078271 |
| MONDO: | |
| Tissue: | Cartilage |
| Tissue Ontology ID: | UBERON:0002418 |
| Cell Source: | Chondrocytes |
| CVCL ID: | |
| Cell Type: | chondrocyte |
| Cell Ontology ID: | CL:0000138 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C, RNA-seq |
| Low Throughput Method: | 3C, RT-RT-qPCR, CRISPR Knockout |
About Target Gene
| Target gene : | EREG |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00619 | chr4:75700000-76000000 | Blood | B lymphoblast | -- |
| E_00736 | chr4:75700000-76000000 | Colon | colon epithelial cell | -- |
| E_00737 | chr4:75700000-76000000 | Colon | colon epithelial cell | -- |
| E_00605 | chr4:75746565-75746914 | Bone Marrow | patient-derived xenograft B-ALL cell | B-cell acute lymphoblastic leukemia |
| E_00735 | chr4:75746565-75746914 | Colon | colon epithelial cell | -- |
Expression of Target Genes for the Enhancer