About Enhancer
| Enhancer ID: | E_00620 |
| Species: | Homo sapiens |
| Position : | chr4:76191350-76202240   |
| Year: | 2019 |
| Title: | The SNP of rs6854845 suppresses transcription via the DNA looping structure alteration of super-enhancer in colon cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 31078271 |
| MONDO: | |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Human normal colon epithelial cell |
| CVCL ID: | |
| Cell Type: | colon epithelial cell |
| Cell Ontology ID: | CL:1000348 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-RT-qPCR, CRISPR knockout |
About Target Gene
| Target gene : | EREG |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00209 | chr4:76192040-76237727 | Inner cell mass | embryonic stem cell | -- |
| E_00213 | chr4:76192040-76237727 | Brain | glioblastoma cell | glioblastoma |
| E_00621 | chr4:76192040-76237727 | Colon | colon epithelial cell | -- |
| E_00992 | chr4:76192040-76237727 | Lung | non-small cell lung carcinoma cell | non-small cell lung carcinoma |
Expression of Target Genes for the Enhancer