About Enhancer
| Enhancer ID: | E_00637 |
| Species: | Homo sapiens |
| Position : | chr11:63800000-63802500   |
| Year: | 2023 |
| Title: | Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | endometrial adenocarcinoma |
| PMID: | 37832549 |
| MONDO: | MONDO:0005047 |
| Tissue: | Endometrium |
| Tissue Ontology ID: | UBERON:0001295 |
| Cell Source: | MFE-296 |
| CVCL ID: | CVCL_1406 |
| Cell Type: | endometrial adenocarcinoma cell |
| Cell Ontology ID: | CL:0000069 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay |
| High Throughput Method: | Hi-C, RNA-seq |
| Low Throughput Method: | CRISPRa, Western blot |
About Target Gene
| Target gene : | OSKM |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00422 | chr11:63800000-63802500 | Connective Tissue | mesenchymal progenitor cell | -- |
Expression of Target Genes for the Enhancer