Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00656
Species: Homo sapiens
Position : chr8:128910869-128911521
Year: 2024
Title: Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  38760567
MONDO: MONDO:0011998
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Functional perturbation assay
High Throughput Method: RNA-seq
Low Throughput Method: CRISPRi, Flow Cytometry, qRT-PCR
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_00167 chr8:128750000-129000000 Breast breast carcinoma cell breast carcinoma
Expression of Target Genes for the Enhancer