About Enhancer
| Enhancer ID: | E_00698 |
| Species: | Homo sapiens |
| Position : | chr6:31132200-31132800   |
| Year: | 2018 |
| Title: | The TFAP2C-regulated OCT4 naive enhancer is involved in human germline formation |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30590035 |
| MONDO: | |
| Tissue: | Gonadal Tissue |
| Tissue Ontology ID: | UBERON:0000991 |
| Cell Source: | hPGCLC |
| CVCL ID: | |
| Cell Type: | primordial germ cell-like cell |
| Cell Ontology ID: | CL:0000670 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | POU5F1 |
About TF
| TF name : | TFAP2C |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TFAP2C | Validated transcriptional targets of TAp63 isoforms | pid | 54 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer