About Enhancer
| Enhancer ID: | E_00716 |
| Species: | Homo sapiens |
| Position : | chr11:69616543-69628302   |
| Year: | 2025 |
| Title: | p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Ewing sarcoma |
| PMID: | 40890402 |
| MONDO: | MONDO:0003368 |
| Tissue: | Bone |
| Tissue Ontology ID: | UBERON:0001474 |
| Cell Source: | SKNMC cells |
| CVCL ID: | CVCL_0530 |
| Cell Type: | Ewing sarcoma cell |
| Cell Ontology ID: | CL:0000050 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR, dTAG degradation assay |
About Target Gene
| Target gene : | CCND1 |
About TF
| TF name : | EWS::FLI1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer