Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00746
Species: Homo sapiens
Position : chr11:5278952-5279402
Year: 2017
Title: Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  28416141
MONDO: MONDO:0011998
Tissue: Bone marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: K-562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: CRISPRi-based single-cell enhancer perturbation
High Throughput Method: Drop-seq single-cell RNA-seq, CRISPR barcoding
Low Throughput Method: qRT-PCR, and ChIP-qPCR
About Target Gene
Target gene : HBG2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer