About Enhancer
| Enhancer ID: | E_00761 |
| Species: | Homo sapiens |
| Position : | chr16:1600000-1600110   |
| Year: | 2000 |
| Title: | Loading of DNA-Binding Factors to an Erythroid Enhancer |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic myeloid leukemia |
| PMID: | 10688646 |
| MONDO: | MONDO:0011998 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K562 Erythroleukemia Cells |
| CVCL ID: | CVCL_0004 |
| Cell Type: | chronic myeloid leukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, RT-RT-qPCR, EMSA |
About Target Gene
| Target gene : | HBA1 |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer