About Enhancer
| Enhancer ID: | E_00777 |
| Species: | Homo sapiens |
| Position : | chr21:36759535-36828803   |
| Year: | 2024 |
| Title: | Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 39643619 |
| MONDO: | |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | hiPSC-derived iMSCs |
| CVCL ID: | |
| Cell Type: | mesenchymal stromal cell |
| Cell Ontology ID: | CL:0000134 |
| Experiment Type: | Functional perturbation assay, Chromatin interaction assay, In vivo functional assay |
| High Throughput Method: | 3C-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR |
About Target Gene
| Target gene : | SETD4 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00774 | chr21:36759535-36828803 | Bone Marrow | mesenchymal stromal cell | -- |
| E_00775 | chr21:36759535-36828803 | Bone | osteoblast | -- |
| E_00776 | chr21:36759535-36828803 | Bone | mouse calvarial cell | -- |
| E_00778 | chr21:36759535-36828803 | Bone | osteoblast | -- |
| E_00779 | chr21:36759535-36828803 | Bone | mouse calvarial cell | -- |
Expression of Target Genes for the Enhancer