About Enhancer
| Enhancer ID: | E_00779 |
| Species: | Mus musculus |
| Position : | chr4:115040426-115042426   |
| Year: | 2016 |
| Title: | Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26809507 |
| Cell Source: | HPC-7 |
| CVCL ID: | CVCL_RB19 |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation |
| High Throughput Method: | ChIP-seq; Hi-C |
| Low Throughput Method: | ChIP-qPCR/ChIP; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Tal1 |
About TF
| TF name : | Egr1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Egr1 | AP-1 transcription factor network | pid | 71 |
| Egr1 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
| Egr1 | Downstream signaling in naïve CD8+ T cells | pid | 69 |
| Egr1 | ErbB1 downstream signaling | pid | 105 |
| Egr1 | Glucocorticoid receptor regulatory network | pid | 85 |
| Egr1 | Interferon alpha/beta signaling | reactome | 67 |
| Egr1 | Regulation of Androgen receptor activity | pid | 54 |
| Egr1 | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | pid | 80 |
| Egr1 | Signaling events mediated by PRL | pid | 23 |
| Egr1 | TCR | netpath | 261 |
| Egr1 | Trk receptor signaling mediated by PI3K and PLC-gamma | pid | 36 |
| Egr1 | Trk receptor signaling mediated by the MAPK pathway | pid | 34 |
| Egr1 | Prion diseases | kegg | 34 |
| Egr1 | Hs_Thyroid_Stimulating_Hormone_(TSH)_signaling_pathway_WP2032_89823 | wikipathways | 28 |
| Egr1 | Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 | wikipathways | 15 |
| Egr1 | Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 | wikipathways | 44 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
15 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00775 | chr4:115040426-115042426 | NA | NA | NA |
| E_00776 | chr4:115040426-115042426 | NA | NA | NA |
| E_00777 | chr4:115040426-115042426 | NA | NA | NA |
| E_00778 | chr4:115040426-115042426 | NA | NA | NA |
| E_00780 | chr4:115040426-115042426 | NA | NA | NA |
| E_00781 | chr4:115040426-115042426 | NA | NA | NA |
| E_00782 | chr4:115040426-115042426 | NA | NA | NA |
| E_00783 | chr4:115040426-115042426 | NA | NA | NA |
| E_00784 | chr4:115040426-115042426 | NA | NA | NA |
| E_00785 | chr4:115040426-115042426 | NA | NA | NA |
| E_00786 | chr4:115040426-115042426 | NA | NA | NA |
| E_00787 | chr4:115040426-115042426 | NA | NA | NA |
| E_00788 | chr4:115040426-115042426 | NA | NA | NA |
| E_00789 | chr4:115040426-115042426 | NA | NA | NA |
| E_00790 | chr4:115040426-115042426 | NA | NA | NA |
Expression of Target Genes for the Enhancer